Dose Course 2018_Flipping book

DCH as optimization criteria

90% iso-probability line, DVH

Systematic error

90%

• •

Sampled from normal distribution

DCH

98%

Used to shift the CTV

Random error

• • •

Normal distribution

Infinite number of fractions Convolution of dose (or fluence)

Calculate DVH for CTV One entire treatment course

• •

Repeat for N treatments

Create coverage map

D

D

98%

presc

Example of optimization objective:

≥

≥ %

%

Gordon et al., Med Phys 37:550, 2010