EBRO 2017

Esophageal cancer: Neo-adjuvant Chemoradiotherapy or Chemotherapy?

EBRO 2017

Neo-adjuvant chemoradiotherapy: 40 Gy + Cisplatin 100 mg/m 2 d1 + 5FU 750 mg/m 2 d1-5 x3 RESECTION

R A N D O M

N=180

T1N1M0 or T2-3N0-1M0

Primary endpoint: Pathologic complete response (pCR)

AC (73%) SCC (27%)

Neo-adjuvant chemotherapy: Cisplatin 100 mg/m 2 d1 + 5FU 750 mg/m 2 d1-5 x3 RESECTION

Klevebro et al. Ann Oncol 2016