EBRO 2017

Definitive chemoradiotherapy in locally advanced esophageal cancer

RTOG 94-05

EBRO 2017

Chemoradiotherapy (standard RT dose) (50.4 Gy + cisplatin/5FU) N= 109

R A N D O M

T1-T4, N0-N1 M0 SCC and AD

Primary endpoint: Survival

Chemoradiotherapy (high RT dose)

(64.8 Gy + cisplatin/5FU) N= 109

higher radiation dose does not improve outcome

Minsky et al. J Clin Oncol 2002