EBRO 2017

BRCA1 and BRCA2 Tumors Characteristics: Genome

28 BRCA1 BLC

100%

20% 20%

Frequency

1

2 3 4 5 6 7 8 9 10 11 12 13141516 17 1819202122

28 sporadic BLC

100%

20% 20%

Frequency

1

2 3 4 5 6 7 8 9 10 11 12 13141516 17 18192021

22

Tirkkonen et al, Cancer Research, 1997 Van Beers et al, Cancer Research, 2005 Jönsson et al, Cancer Research 2005

Stefansson et al, BCR, 2009 Waddell et al, BCRT, 2009 Manie, Stern, unpublished data