EBRO 2017

Pre-op RT vs selective post-op [C]RT

Study

n

LR p

OS

Uppsala 471 25.5 Gy

13%

No diff

0.02

60 Gy RT 22%

No diff

1980-1985

MRC CR07 1350 25 Gy

4%

No diff

<0.0001

45 Gy CRT 11%

No diff

1998-2005

Dutch TME 1861 25 Gy

6%

64%

<0.001

50.4 Gy RT 11%

63% Frykholm GJ. Dis Colon Rectum. 1993;36(6):564-72 Sebag-Montefiore D, Lancet. 2009;373(9666):811-20 Peeters KC, Ann Surg. 2007 Nov;246(5):693-701

1996-1999