EBRO 2017

Randomized Trial of IMRT vs. Standard RT in early breast cancer

• 306 patients • 50 Gy/25 fractions ± boost 11 Gy/5

Standard

IMRT

p

> 20% of breast >105% of dose Worsen in breast appearance

15%

1%

0.005

58%

40%

0.008

Central breast fibrosis

32%

21%

0.02

Donovan et al. Radiother Oncol, 2007