EBRO 2017

High-grade Glioma Background

• High-grade glioma • Grade 3 – 4 glioma • Astrocytoma and oligodendroglioma • Grade 4 astrocytoma = GBM = WHO Grade 4 glioma • Debate over GBM-O

• Rare tumours • Poor prognosis • Little improvement over time • Surgery and RT mainstay of treatment • Some role for chemo