EBRO 2017

Case 2

• Nordic study

• 291 pts; GBM; >60 yr old • TMZ 200mg/m2 d1-5q28 or • RT 60 in 30 or • RT 34 in 10 • Median OS 8/12 with RT 34 • GBM >70yr old; RT 34 >OS RT 60 • GBM >70yr old; TMZ > OS RT 60

or TMZ (~6/12 with RT 60 )

• GBM >70yr old; RT 34 TMZ • Toxicity non-zero (3 deaths ~1%TRM) ~ OS

Malmstrom LancetOnc 2012