EBRO 2017

Case 4 Management

• Early RT > PFS • Early RT ~ OS

Late RT Late RT

• Early RT ~ RiskTrans

Late RT

• TMZ ~or < OS

RT

• RT + PCV > RT alone

• RTOG 98-02 (1998 – 2002) • RT + PCV > OS

RT (13 vs 7 yrs)

• RT + PCV > PFS

RT

• RT + PCV ~ CogFunct

RT alone

van den Bent Lancet 2005