ESTRO 2021 Abstract Book

S284

ESTRO 2021

Conclusion This preliminary analysis confirmed the possibility to quantitatively study RT-induced alteration of salivary MB in a clinical setting. Despite the mechanisms involved in these MB changes are still unknown, it is clear that some bacteria are more sensitive to radiation exposure. Particularly, as reported in literature, fusobacteria showing a synchronous shift in their abundances throughout RT correlated with the occurrence of severe