ESTRO 2021 Abstract Book

S723

ESTRO 2021

enjoyment of life compared to males (p = 0.002) although there was no other significant difference regarding any other functional interference item. There was no statistically significant association between pretreatment ECOG, chemotherapy, primary tumor location and radiation schedule with any of the functional interference items (Table 1) Figure 1: Mean functional interference improvement in different functional interference items according to treatment response one month after radiotherapy

Table 1: Changes in mean functional interference scores pre- and post-treatment according to different clinical and treatment variables

Conclusion There is significant correlation between pain reduction and improvement in functional interference items (including physical and psychosocial aspects) in patients with bone metastasis undergoing palliative RT, regardless of treatment fractionation and pretreatment clinical variables (such as age, gender, ECOG, tumor