ESTRO 2021 Abstract Book
S796
ESTRO 2021
not clearly visible on the b500 image due to very small residual volume (<1ccm for GTV-P and GTV-N). These time points were therefor excluded from the analysis.
Table1: mean changes of volume and ADC for GTV-P and GTV-N from baseline to last week of therapy
GTV-P
GTV-N
Decrease of Volume [%]
Mean ADC change [%]
Decrease of Volume [%]
Mean ADC change [%]
pat#1 80.2
36.0
66.9
6.5
pat#2 60.4
44.3
34.8
20.3
pat#3 82.5
11.2
75.2
15.0
pat#4 70.5
60.5
57.3
5.9
pat#5 82.3
72.6
n.a.
n.a.
pat#6 79.3
69.5
75.7
25.1
media n
79.7
52.4
66.9
15.0
Conclusion This data shows early clinical experience to collect serial DWI for HNC patients treated on a 1.5 T MRL during the course of RT. Treatment response by means of ADC can be monitored and offers the potential for future biological response adaptive interventions. Voxel-based ADC-analysis and assessment of individual LN as well as expansion of the cohort are ongoing.
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