ESTRO 2022 - Abstract Book

S1112

Abstract book

ESTRO 2022

Results A cohort of 64 patients (34% males, 66% females) was enrolled. Median age at diagnosis was 65.6 years (range 43-87.8). 5 patients (8%) were HIV+. Two image sets were discarded due to pixel spacing inconsistency. 14030 features spatial dimension were obtained. A cross correlation matrix was set up in order to reduce features collinearity and spatial dimension (p Pearson <0.3). From the original 14030 features space, 3 features were lastly selected (F_stat.kurt+2.9; F_cm.joint.avg+3.1 and F_cm_merged.joint.entr+3.1) and a conditional tree model to identify which feature better separates the Kaplan Meier curves at the Log Rank test.F_stat.kurt+29 appeared to be the best performing feature, and its best threshold level was identified as 2.746 (p=0.025). Figure 1b reports the curves linked to the proposed values.