ESTRO 2022 - Abstract Book

S1146

Abstract book

ESTRO 2022

organs and the D90, D95 and D98 values obtained by HRCTV; also the doses of 0.1 cc, 1 cc and 2 cc of each critical organ like bladder, rectum and sigmoid were recorded separately. Paired sample t-test was used to determine the statistical difference between both planning DVH parameters, p>0.05 was considered significant. Results RESULTS: The median age of the patients was 60 years (35-79). The median ECOG performance score was 1 (0-2) and 75% (n=15) had additional comorbidities. Half of the patients were obese, and the median body mass index (BMI) in all patients was 34 kg/m2 (20-40). Vaginal cuff BRT was applied to 16 patients diagnosed with endometrial cancer and 4 patients with cervical cancer. Median 50.4 Gy (45-50.4 Gy) external RT was applied to 12 patients with a total of 15 Gy BRT boost in 3 fractions. A total of 27.5 Gy HDR-BRT in 5 fractions was applied to 8 endometrial cancer patients. No significant difference was found between target and critical organ volumes when the DVH parameters of the planning with and without the Foley catheter were evaluated. In addition, no statistically significant difference was found between the two plans in terms of target and critical organ doses such as HRCTV D90, D95, D98 and D0.1, D1, D2cc of critical organs. DVH information related to volume and doses are summarized in Table-1. Table-1. Dosimetric analysis of target volumes and organs at risk

Conclusion CONCLUSION: It is not necessary to empty the bladder by inserting a Foley catheter before the vaginal cuff BRT treatment.It seems to be sufficient to simulate and treat the patient by just emptying the urine.

PO-1351 Metachronous vulvar cancers among patients with previously treated cervical cancer

M. P ł achta 1,2

1 Greater Poland Cancer Centre, Radiotherapy and Gynecologic Oncology Department, Pozna ń , Poland; 2 Poznan University of Medical Sciences, Electroradiology Department, Pozna ń , Poland Purpose or Objective Vulvar cancer is a rare gynaecological cancer. It accounts for only 0,7% of all cancers in women. Usual-type of vulvar intraepithelial neoplasia is associated with persistent HPV infection, thus it appears in younger women. The aim of this study was to present the incidence of coexisting metachronous vulvar cancer among patients with cervical cancer treated in our institute. Materials and Methods 537 patients with vulvar cancer were treated in our Cancer Centre from 2000 to 2020. In 44 women (8,2%) other synchronous or metachronous cancers were found. Results Seven patients (1,3%) were diagnosed with cervical cancer before vulvar cancer. Six of them underwent radical histerectomy. One patient was treated with radical radiotherapy. Mean time between treatment of cervical cancer and vulvar cancer diagnosis was 30,6 years (15-49). None of the patients developed cervical cancer recurrence. Vulvectomy was