ESTRO 2022 - Abstract Book

S1221

Abstract book

ESTRO 2022

31 children with median age of 38 month at diagnosis were treated with RT as a radical aim. All patients received 21 Gy in 14 sessions with IMRT (intensity-modulated radiotherapy). In the analysis by subgroups, we only found a significant decrease (p value = 0.034) in CrCl in patients below four years old treated with RT (n = 16), however, the values remained within the non-pathological physiological range (Table 1). A post-hoc intergroup analysis compared the means of the three laboratory determinations (before treatment, one month after treatment and at the end of follow-up) without finding significant differences (Table 2). The main side effects in the imaging tests were renal atrophy (32.3%), increased vertebral uptake (16.1%) and scoliosis (3.2%). Moreover, two patients (6.4%) developed arterial hypertension that required treatment. No patient developed significant renal dysfunction.

Table 1

Table 2

Conclusion