ESTRO 2022 - Abstract Book

S1614

Abstract book

ESTRO 2022

Materials and Methods Data obtained retrospectively from 57 patients with Choroidal Melanoma treated with episcleral brachytherapy with I-125 from April 2007 to December 2019 in a single institution. Treatment was applied with COMS type plaques loaded with I- 125 seeds, the dose prescribed was 85 Gy, following the COMS (Collaborative Ocular Melanoma Study) recommendations. Patients with a negative extension diagnosis and a minimum follow-up of at least 6 months were included.

Results The average age was 62 years (37-95). Most of the tumors were medium size (86%). Local control was achieved at 42 months of 88.3% (73.4% - 95.1%), metastasis-free survival at 24 months of 92.5% (78-97.6%) and at 36 months of 85.5% (67.7% - 93.9%). Overall survival at 45 months was 85.2% (66.6- 93.8%). Preservation of the eyeball was successful in 82.5%. The most frequent side effects were cataracts (48.8%), radiation retinopathy (14.6%), vitreous hemorrhage (9.8%) and retinal detachment (9.8%).

Conclusion Episcleral brachytherapy is an effective treatment for choroidal melanoma avoiding enucleation.

PO-1812 Therapeutic possibilities in the radiation treatment of NMSC: brachytherapy vs. electrons therapy

C. Camacho Fuentes 1 , C. Sánchez Cortés 1 , M. Calderó Torra 1 , M.L. Ferrández Millán 1 , M. Gascón Ferrer 1 , L. Sopeña Sanz 1

1 Lozano Blesa Clinical Universitary Hospital, Radiation Oncology, Zaragoza, Spain

Purpose or Objective The incidence of skin cancer has been increasing in recent decades, with an estimated 2-3 million non-melanoma skin cancer (NMSC) occurring annually globally. There are different treatment modalities for this pathology, with brachytherapy (BT) playing a fundamental role. The main objective of this work is to compare the toxicity profile, aesthetic results and local control of patients with non-melanoma skin cancer treated with skin brachytherapy with Leipzig applicator versus those treated with electron therapy (ET) at the Lozano Blesa Clinical Universitary Hospital.

Materials and Methods