ESTRO 2022 - Abstract Book

S1651

Abstract book

ESTRO 2022

of the GTV was 13 mm(range: 4-67). We delivered 50-60Gy in 5 fx. in 29/70, 39Gy in 6 fx. in 1/70, 42Gy in 7 fx. in 1/70, 48Gy in 8fx. in 38/70 and 60Gy in 10 fx. in 1/70.The SBRT was delivered every 2 days and the median BED was 105Gy (range 62.4-132, α / β =10Gy).Median follow-up was 24 months (range: 3.9-84.9).7 pts presented a progression of the irradiated lesion. The 2-year local control (LC) was 98.4% (95%CI: 89.5-98.9). Noteworthy, we did not see any difference in terms of 2-year LC between lesions treated with or without biopsy (97.9% in both the groups, p-value=0.26). 33 pts presented a lung progression. The pulmonary relapse-free survival rate was 67% (95%CI: 52.9-77.8) in 2 years.The analysis of the 52 biopsied lesions (32 metastases and 20 primary lung cancers) showed an equivalent 2-year LC (100% vs 95%,respectively; p-value=0.18), but the 2-year lung relapse-free survival rate was 66% for pts with primary cancer and 56% for pts treated for lung metastases (p- value=0.08). The 2-year nodal relapse free survival rate was 67.5% (95%CI:71.1-91.4). In terms of acute toxicity >2, we recorded 2 cases of G2 dysphagia and 10 of G2 asthenia. In terms of late toxicity >2, we recorded 1 case of cough, 1 case of G2 lung toxicity and 10 of G2 asthenia. We also recorded 11 cases of late G3-4 dyspnoea, but only in pts with pulmonary disease progression. In the absence of radiological signs of radiation-induced pneumonia in these 11pts, we attributed the dyspnoea to the progression of the disease. Conclusion This retrospective series confirms the efficacy and safety of SBRT and its role as a therapeutic alternative for non-operable primary or metastatic cancer patients. 1 Gloucestershire Hospitals NHS Foundation Trust, Oncology , Cheltenham, United Kingdom; 2 Gloucestershire Hospitals NHS Foundation Trust, Oncology, Cheltenham, United Kingdom Purpose or Objective Radiotherapy is poorly understood by clerical members of the healthcare team although they communicate frequently with patients who receive this. An online e-Learning module has been developed by Trinity College, Dublin for patients due to undergo radiotherapy. This is available periodically and is openly accessible via the website Future Learn. It is separated into components covering topics such as basic theoretical science, the patient journey through treatment and potential side effects. It was proposed that clerical staff may increase their knowledge and confidence by completing the module. Materials and Methods Volunteers completed a questionnaire prior to commencing the module. On completion two further questionnaires were completed – one repeating the intial one, investigating understanding, and the other assessing the e-learning itself to establish which factors had influenced their experience using a validated survey. Results 7 members of the clerical team at Gloucestershire Oncology Centre volunteered for the study. Of these 2 were unable to complete the module as intended, both citing work commitments. None of the participants had any prior training in radiotherapy. Table 1. demonstrates the mean scores for attitudes and knowledge on a scale of 1-10 before and after completing the module. The written feedback received from those who completed the module was very positive e.g., “very useful to consolidate current knowledge and gain further awareness” and “definitely improved my understanding”. Poster (digital): RTT service evaluation, quality assurance and risk management PO-1862 E-leaning module effect on knowledge and confidence of clerical staff regarding radiotherapy J. Cohen 1 , K. Benstead 2

When asked to score from 1-10 the means were: Motivation of the participants to complete the module - 8.6