ESTRO 2022 - Abstract Book

S1675

Abstract book

ESTRO 2022

blending at the patient level was performed guaranteeing that, among contours being evaluated per patient and OAR, the 50%-50% split was satisfied. Experts were asked to score ACs and the contours from clinical experts (CE) as A/acceptable, B/ acceptable after minor corrections, and C/ not acceptable for clinical use. To avoid any bias, experts were blind to the origin of the contours (manual or AI). Results Average Dice score coefficient (DSC) for ART-Net® on the testing set was 72.6% while that of the inter-expert variability was 69.1%. ART-Net® achieved mean dice greater than the inter-expert variability for all 25 organs (Tab.1). Encephalon reported the highest DSC 97.45 ± 0.50, while left vestibular and semi-circular canals (VSCC) reported the lowest DSC of 52.58 ± 14.55. These organs are normally not visible on T1Gd sequences, which might explain these results. 4 out of the 9 organs were evaluated as A for 100% of the cases. All 9 OARs achieved a 100% A+B score for the AI contours. A+B score for the manual delineation from experts was 100% for all but one organ (left eye lens).

Conclusion In this study, we investigated the advantages of using a CE-marked, FDA-cleared anatomically preserving deep-learning ensemble architecture for automatic segmentation of OARs for brain RT on MRI. This work illustrates the strength of using ART-Net® for segmentation to support MR-based treatment planning in the brain as it consistently generates delineations with high clinical acceptability which can lead to reduction in variability of practice. Future work will include dosimetric evaluations.

PO-1891 Impact of internal mammary chain irradiation on heart subvolumes doses in breast cancer radiotherapy

Z. Naimi 1 , E. Bennour 2 , H. Neji 3 , M. El Bessi 1 , R. Ben Amor 1 , M. Bohli 1 , J. Yahyaoui 1 , L. Kochbati 1

1 Abderrahmen Mami Hospital Ariana, Radiation Oncology Department, Ariana, Tunisia; 2 Abderrahmen Mami Hospital Ariana, Cardiology Department, Ariana, Tunisia; 3 Abderrahmen Mami Hospital Ariana, Radiology Department, Ariana, Tunisia Purpose or Objective The aim of this study was to analyse the impact of internal mammary chain (IMC) irradiation on coronary arteries and cardiac subvolumes exposure in breast cancer (BC) RT.