ESTRO 2022 - Abstract Book

S482

Abstract book

ESTRO 2022

The median OS, bPFS and rPFS for the whole group were 9.3 (95% CI: 8.8-NR), 8.4 (95% CI: 8.3-NR) and 8.5 years (95% CI: 8.4-NR) respectively. The effect of prostate RT (± pelvic nodal RT) was analyzed within a multivariable analysis model, adjusting for age, PSA, Gleason score, T stage, PS and ADT, RT improved OS [HR = 0.39 (0.17-0.90) p= 0.028 ] , bPFS [HR=0.27 (0.13-0.53) p <0.001 ] and rPFS [HR=0.23 (0.10-0.50)) p = 0.001 ] (figure 2). Gleason grade group 5 was found to be an independent prognostic factor for OS [HR=2.09 (1.33-3.29) p=0.001 ] after adjusting for other variables. No other tumour or treatment factors were found to be significant.