ESTRO 2022 - Abstract Book

S493

Abstract book

ESTRO 2022

The main result, 73% of cervical cancer patients studied might be adequately treated with eBT and based on CT images, is quite important result. Electronic brachytherapy treatments allow bunker-free treatment of cervical cancer with optimistic results for patients with multiple stages and significant HR-CTV volumes. We believe they are a plausible option for LMICs due to their ease of use, portability, and versatility. At our centre we have extensive experience with this technique in endometrial, breast, cervical and skin cancer treatments.

PD-0562 Source path verification - Advanced Gynecological Brachytherapy Applicator (Venezia)

H. Vaithianathan 1 , T. Kupfer 2

1 Olivia Newton-John Cancer Research & Wellness Centre , Radiation Oncology, Heidelberg, Victoria, Australia; 2 Olivia Newton-John Cancer Research & Wellness Centre, Radiation Oncology, Heidelberg, Victoria, Australia Purpose or Objective The department purchased first set of Elekta’s Advanced Gynecological Applicator (AGA, “Venezia”) in 2017. Since then, three AGA sets are added in 3 years. This work’s aim was to verify the accuracy of Oncentra, brachytherapy TPS’s modelled source (ver 4.6.0) dwell position (DP) against the actual source position especially in lunar ovoids curved source path, prior to clinical use. Materials and Methods AGA consists of two lunar shaped ovoids (LO) along with intrauterine (IU) tandem. Three sizes of LO (22, 26 and 30 mm, inner lumen 3 mm diameter) and several IU tube lengths can be configured to accommodate various patient anatomies, while vaginal and perineal interstitial needles (Proguide 6F Round 294mm) allow conformation of the dose to the individual tumor shapes. DP verification in the IU tandems was done using autoradiographs (RTQA film). While in a lunar applicator, with source dwelling at various positions in a curved path, the centre of the source may not be exactly at the centre of the lumen. However, with bulky LO, the film is too far from the source DP resulting in unacceptable uncertainties in source localization on autoradiographs. Instead, the position of the source within the LO was radiographed with a mobile x-ray unit and a computed radiography (CR) plate. For each LO, four DP were imaged separately to preserve image fidelity whilst avoiding saturation of the CR-detector. A composite image was then created in MatLab using grey-scale based image registration. Finally, the composite image was overlaid over an image created in Oncentra, which showed a detailed outline of the LO model inclusive of the modelled source DP (Nucletron Applicator Library Manager ver 1.0.1.1). The 2D vector distance between the imaged source and the corresponding model DP was measured, along with the offset. Further commissioning tests of the applicator included physical integrity checks, overall match of the applicator’s CT image to the applicator model and determining the distance of the most distal DP to the tip of the needle or to the tip of the applicator (offset). Results The physical source does not travel at the centre of the LO lumen, rather, it touches the wall of the lumen in different places as it advances into the ovoid (figure). This is partially reflected in the modelled DP, which agreed to within 1 mm with the centre of the source. The measured offsets (approximately 0.6mm) for IU tube, LO and the 6F needle were within 1 mm of vendor specifications. The CT images of the applicators matched the model well.