ESTRO 2022 - Abstract Book

S563

Abstract book

ESTRO 2022

At a median follow-up of 26 months (IQR 14-38 months) 5 (11.6%) patients on W&W had local regrowth (2 also with distant metastasis). All except 1 were surgically salvaged. Overall organ preservation rate was 39%. The only factor influencing cCR/nCR was baseline T and N stage. Of the 15 T2 ttumors 12(80%) had cCR whereas of the 85 T3 tumors 38 (45%) had cCR/nCR (p_0.02). Similarly absence of mesorectal nodes was associated with higher cCR/nCR rate (73% vs 46%, p_0.04) Late rectal toxicity was observed in 12 (25%) patients with 6 having Grade 1 and another 6 Grade 2. DFS. Overall survival being 100% Overall 8(8%) developed distant metastasis 4 from the WW group and 4 from PR group. Conclusion : Endorectal brachytherapy is a safe and feasible technique to enhance complete response, reducing local regrowth and thus improving organ preservation for distal rectal cancers.

Conclusion Conclusion : Endorectal brachytherapy is a safe and feasible technique to enhance complete response, reducing local regrowth and thus improving organ preservation for distal rectal cancers

OC-0633 Endorectal contact radiation boosting: making the case for dose and volume reporting.