ESTRO 2022 - Abstract Book

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Abstract book

ESTRO 2022

of the three RBE models, lowering the α / β increased the biological doses, with the effect being in the same range as the differences between the models (Fig 2b).

Conclusion Accounting for the potentially variable RBE in proton therapy of high-risk prostate cancer resulted in increases in relative volumes of up to 8% at the dose levels corresponding to the trial dose/volume constraints. The choice of model and the choice of input parameter had similar effects. The biological doses obtained with the LWD were closest to the constant RBE. Biological doses including variable RBE will be assessed prospectively in our trial.

PD-0730 Automated beam angle selection in proton therapy for liver lesions using an AI approach

R. Kaderka 1 , K. Liu 2 , L. Liu 3 , R. Van der Straeten 4 , T. Liu 2 , K. Lee 2 , E. Tu 2 , I. MacEwan 3 , D. Simpson 5 , J. Urbanic 3 , C. Chang 3

1 University of Miami School of Medicine, Radiation Oncology, Miami, USA; 2 Taiwan AI Labs, Taiwan AI Labs, Taipei, Taiwan; 3 California Protons Cancer Therapy Center, Radiation Oncology, San Diego, USA; 4 Varian Medical Systems, Varian Medical Systems, Palo Alto, USA; 5 University of California, San Diego, Department of Radiation Oncology and Applied Sciences, La Jolla, USA Purpose or Objective This study evaluates the performance of an AI to automate beam angle selection for liver lesions treated with scanned proton beams.

Materials and Methods