ESTRO 2022 - Abstract Book

S69

Abstract book

ESTRO 2022

Conclusion We have developed a method for fast robust optimization of PBS arc plans. When utilizing energy layer sequencing with a penalty on the number of upward jumps, it is more favorable to deliver the arc over two revolutions. The two-beam arc approach results in high-quality plans, which can be optimized and delivered in a few minutes.

Proffered Papers: Normal tissue radiobiology

OC-0094 Beam pulse structure affects the magnitude of Flash effect in zebrafish embryo

E. Beyreuther 1,2 , J. Pawelke 3,4 , M. Brand 5 , S. Hans 5 , K. Hideghéty 6,7 , J. Jansen 8,9 , L. Karsch 2,4 , E. Lessmann 1 , S. Löck 10,11,12 , M. Schürer 13 , J. Seco 14,9 , E.R. Szabo 15 , U. Schramm 16 1 Helmholtz-Zentrum Dresden - Rossendorf, Institute of Radiation Physics, Dresden, Germany; 2 Oncoray - National Center for Radiation Research in Oncology, Laser-Radiooncology, Dresden, Germany; 3 Oncoray - National Center for Radiation Research in Oncology, Laser-Radiooncology , Dresden, Germany; 4 Helmholtz-Zentrum Dresden - Rossendorf, Institute of Radiooncology - OncoRay, Dresden, Germany; 5 Technische Universität Dresden, Center for Regenerative Therapies TU Dresden and Cluster of Excellence 'Physics of Life',, Dresden, Germany; 6 University of Szeged, Oncotherapy Department, Szeged, Hungary; 7 ELI-HU Non-Profit Ltd, ELI Alps, Szeged, Hungary; 8 German Cancer Research Center, Division of Biomedical Physics in Radiation Oncology, Heidelberg, Germany; 9 Ruprecht-Karls-University Heidelberg, Faculty of Physics and Astronomy, Heidelberg, Germany; 10 Oncoray - National Center for Radiation Research in Oncology, Modeling and Biostatistics in Radiation Oncology, Dresden, Germany; 11 Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Department of Radiotherapy and Radiation Oncology, Dresden, Germany; 12 German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, German Cancer Consortium (DKTK), Partner Site Dresden, Dresden, Germany; 13 German Cancer Research Center, National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany; 14 German Cancer Research Center, Division of Biomedical Physics in Radiation Oncology, Dresden, Germany; 15 ELI-HU Non-Profit Ltd, ELI Alps, Szeged, Hungary; 16 Helmholtz-Zentrum Dresden - Rossendorf, Institute of Radiation Physics , Dresden, Germany

Purpose or Objective