ESTRO 2022 - Abstract Book

S954

Abstract book

ESTRO 2022

Conclusion The acoustic features enable to discover interpretable differences between voluntary and reflexive coughs, which demonstrates the relevance of the features. Also, the contrast between voluntary and reflexive coughs suggests that both should be considered in future work oriented towards discovering biomarkers of aspiration in patients with RAD.

PO-1122 Prospective assessment of diurnal variation of Xerostomia in treated head neck cancer (HNC) patients

S. Agarwal 1 , A. Doshi 2 , R. Patel 3 , M. Roy 4 , N. Kalyani 5

1 Jaslok hospital and research centre, Radiation Oncology, Mumbai, India; 2 Jaslok Hospital and Research Centre, Radiation Oncology, Mumbai, India; 3 Jaslok Hospital and Research Centre, Radiation oncology, Mumbai, India; 4 Jaslok Hospital and research Centre, Radiation oncology, Mumbai, India; 5 Jaslok Hospital and research centre, Radiation Oncology, Mumbai, India Purpose or Objective The objective is to assess diurnal variation in xerostomia post curative intent radiotherapy / chemoradiotherapy in HNC patients and possibly to identify factors (the patient, tumor and treatment factors) influencing it. Materials and Methods HNC squamous cell carcinoma of treated with curative intent & who completed minimum 6 months, disease free were enrolled in this study. Patients were treated with radical or adjuvant external beam radiotherapy with conventional or volumetric arc radiotherapy (VMAT) with or without concomitant chemotherapy. Xerostomia evaluation was done using Groningen radiation induced xerostomia (GRIX scale) questionnaire by each patient once, on follow-up. On GRIX scale, a 14-question questionnaire were filled by the patient. The responses were recorded and analysis was done using SPSS. Xerostomia correlation of variables with patient, tumor and treatment factors was done. Results In our study of 100 consecutive treated cases of head and neck cancer patients on follow-up, we aimed to evaluate diurnal variation in xerostomia and factors affecting xerostomia. Our cohort comprised majority of oral cavity cancer patients with buccal mucosa and gingivo-buccal complex lesions being the commonest sub site. Seventy one patients received adjuvant radiation, remaining definitive radiotherapy. Fifty eight patients were treated with VMAT technique remaining with conventional technique.Fifty eight patients were evaluated within 1 year post radiation.Thirty five patients had moderate