ESTRO 2022 - Abstract Book

S982

Abstract book

ESTRO 2022

Figure 1 - 3-tiered Prognostic Scores achieving the highest partial likelihood within the entire cohort; Calculation of the Performance Status Score (see within Performance Status Score lower left)

Conclusion Although recent scores incorporating laboratory parameters show the best performance in predicting overall survival, scores relying on clinical parameters only are still valid and appealing as they are easier to calculate and as the difference in overall performance is negligible. A score based only on performance status shows an excellent overall performance and thus is favored for universal use of a BM score for decision-making.

PO-1158 Re-irradiation with Stereotactic Radiotherapy for Recurrent High Grade Glial Tumors

E. Delikgoz Soykut 1 , E. Odabasi 1 , N. Sahin 1

1 Samsun Training and Research Hospital, Radiation Oncology, Samsun, Turkey

Purpose or Objective Despite the radical treatments applied, local recurrence is encountered in the majority of high-grade gliomas (HGG). There is no standard treatment when recurrence is detected, but stereotactic radiotherapy (SRT) is a preferable alternative in this context. The aim of this retrospective study is to evaluate the efficacy of SRT for recurrent HGG, and to investigate the factors that affect survival outcomes. Materials and Methods From September 2013 to March 2021, a total of 59 patients with 64 lesions were re-irradiated with CyberKnife stereotactic radiotherapy. The primary endpoints of the study were overal survival (OS), progression free survival (PFS) and local control rates (LCR). Survival curves were estimated with the Kaplan-Meier method and compared using log-rank test, hazard ratios were estimated using Cox regression analysis.

Results