ESTRO 2023 - Abstract Book

S1752

Digital Posters

ESTRO 2023

For each disease site, the beamlet-free optimization algorithm is able to bring a similar target coverage as its opponent using the beamlets, while keeping the dose to the organs within the clinical constraints (Figure 1, liver case). Nevertheless, it is computed in a much more efficient way. For example, it reduces the computation time and the memory usage by 87.5% and 60% respectively in the liver case (Table 1). Moreover, it could be even further improved considering that the beamlet- based optimization was using a coarse grid while the beamlet-free was optimizing on the CT grid .

Conclusion The deployment of SPArc in the clinic could be facilitated by using beamlet-free combined dose computation and optimization in the treatment planning system, which increases the speed and computing efficiency significantly. [1] Ding X et al. Spot-Scanning Proton Arc (SPArc) Therapy: The First Robust and Delivery-Efficient Spot-Scanning Proton Arc Therapy. Int J Radiat Oncol Biol Phys. 2016;96(5):1107-1116. [2] Souris K, Lee JA, Sterpin E. Fast multipurpose Monte Carlo simulation for proton therapy using multi- and many-core CPU architectures. Med Phys. 2016;43(4):1700.