ESTRO 2023 - Abstract Book

S20

Saturday 13 May

ESTRO 2023

Conclusion This observational multicenter study on vulvar cancer exclusive radiotherapy revealed a large variability of doses and treatment’s volumes achieving not quite satisfactory outcome results. For this neoplasm with a poor prognosis, further collaborative prospective research is needed to standardize the RT strategy. MO-0053 Developing National Consensus Recommendations for Vulvar Cancer Radiotherapy Treatment. P. Baird 1 , E. Dyke 2 , M. Powell 3 , A. Taylor 4 , L. Hanna 5 , U. McGivern 6 , J. Summers 7 , A. Gore 8 , A. Cook 9 , J. Forrest 10 , A. Stewart 11 1 St Luke's Cancer Centre , Clinical Oncology , GUILDFORD, United Kingdom; 2 St Luke’s Cancer Centre, Physics Department, GUILDFORD, United Kingdom; 3 Barts Health NHS Trust, Clinical Oncology, London, United Kingdom; 4 The Royal Marsden NHS Foundation Trust, Clinical Oncology, London , United Kingdom; 5 Velindre University Hospital NHS Trust, Clinical Oncology, Cardiff, United Kingdom; 6 Belfast City Hospital, Clinical Oncology, Belfast, United Kingdom; 7 Maidstone and Tunbridge Wells NHS Trust, Clinical Oncology, Maidstone, United Kingdom; 8 Leicester Royal Infirmary, Clinical Oncology, Leicester, United Kingdom; 9 Gloucestershire Hospitals NHS Trus, Clinical Oncology, Gloucester, United Kingdom; 10 Royal Devon University Hospital Trust, Clinical Oncology, Exeter, United Kingdom; 11 Saint Luke's Cancer Centre , Clinical Oncology, GUILDFORD, United Kingdom Purpose or Objective The UK vulvar cancer audit showed the widespread use of IMRT in the UK with minimal organ toxicity. However, there was considerable dose range variation with no UK consensus regarding the minimum dose to improve local control (1). The international consensus guidelines for the contouring and treatment of vulvar cancer do not reflect UK practice (2).We aimed to develop recommendations to deliver consistent RT treatment of vulvar cancer in the UK with greater standardisation of dose prescribing and reporting. Materials and Methods The Royal College of Radiologists (RCR) invited a group of gynaecology Clinical Oncology experts to develop consensus recommendations. Draft guidelines were written using the outcomes of the 2019/2020 RCR national vulvar cancer radiotherapy audit. The Consensus group then refined the guidelines through regular meetings and discussions, using a modified Delphi process. The RCR hosted an online contouring exercise where a second expert panel contoured two vulvar cancer cases (radical radiotherapy alone and post-operative nodal fields) before and after reading the consensus recommendations. Further changes were made and the draft recommendations were presented at a British Gynaecological Cancer Society workshop after which final changes were made. Results Consensus recommendations define volumes to contour (table 1) with structured contouring guidelines containing example images. Figure 1 recommends dose/fractionation schemes. Guidance is also given regarding treatment planning, dosimetric parameters and care on treatment.

Table 1

Figure 1