ESTRO 2023 - Abstract Book

S1112

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ESTRO 2023

Instead for reSBRT the mean prescribed dose was 41 Gy (range 16-50Gy, mean BED α / β 10=92). For 15 pts (79%) the total doses were prescribed to the 80% isodose rather for 4 pts (21%) were prescribed to the dmean covering the 95% of the PTV. The mean tumor volume (the GTV) was 6,8 cm3 (range 1,5-19,9), with median PTV of 13,4 cm3 (range 3,6-34,9). The mean volume encompassed by the prescription isodose was 11,19 cm3. Mean PTV D2 and Mean PTV D98 were 51(range 16,5- 67,5) and 41(range 15-59,5), respectively. The average mean liver dose was 3,9 Gy (range 1-10 Gy; median EQD2 2,9 Gy) and 3,7 Gy (range 1,6-8 Gy; median EQD2 3Gy) for the first SBRT and reSBRT, respectively.

We did not report acute and late toxicities >1 at median follow-up of 10,7 months (range 2-34). At 1 year OS and PFS was 73,08% and 50% respectively, with an ORR and CB were both 54%.

Conclusion MRIg-reSBRT is an effective, safe and valid integrated option in a multi-treatment strategy for patients with an oligometastatic metastatic disease.

PO-1383 Neoadjuvant versus definitive chemoradiation for esophageal cancer: a retrospective analysis

I. Joye 1,2 , S. Vermeulen 3 , T. Op de Beeck 3 , N. Geudens 3 , T. Vandamme 4 , M. Simoens 5 , T. Botelberge 6 , J. Valk 7 , M. de Maat 8 , W. Lybaert 9 , W. Demey 10 , M. Machiels 11 , D. Nevens 1 , C. Billiet 1 , P. Meijnders 1 , C. Mercier 1 , S. Vanderkam 1 , R. Weytjens 1 , S. Van Laere 2 1 Iridium Netwerk, Department of Radiation Oncology, Wilrijk, Belgium; 2 University of Antwerp, Integrated Personalised and Precision Oncology Network, Antwerpen, Belgium; 3 University of Antwerp, Department of Medicine, Antwerpen, Belgium; 4 University Hospitals Antwerp, Department of Oncology, Edegem, Belgium; 5 Ziekenhuis Netwerk Antwerpen (ZNA), Department of Gastroenterology, Antwerpen, Belgium; 6 GasthuisZusters Antwerpen (GZA), Department of Gastroenterology, Wilrijk, Belgium; 7 Ziekenhuis Netwerk Antwerpen (ZNA), Department of Surgery, Antwerpen, Belgium; 8 University Hospitals Antwerp, Department of Surgery, Edegem, Belgium; 9 VITAZ , Department of Oncology, Sint-Niklaas, Belgium; 10 KLINA, Department of Oncology, Brasschaat, Belgium; 11 Iridium Netwerk , Department of Radiation Oncology, Wilrijk, Belgium

Purpose or Objective