ESTRO 2023 - Abstract Book

S1156

Digital Posters

ESTRO 2023

Patient & treatment characteristics LMS (n=32) ESS (n=49)

50

years

41

years

Median age (Range)

(36-72 years)

(20-71 years)

Menopause attained

16 (50%)

15 (30.6%)

FIGO stage

1&2

18(56.25%) 14(43.75%)

30(61.1%) 19(38.9%)

3&4

Grade

Low-grade ESS

27(55%) 22(45%)

High-grade ESS Primary surgery

31(96.9)

49(100%)

Positive surgical margin

12 (37.5%) 9(18.3%)

Pelvic EBRT

10(31.3)

20 (40.8%)

Chemotherapy

17(53.1%) 14 (28.5%)

Figure1: Survival curves for PFS and OS

Conclusion Uterine sarcomas are relatively rare. Advanced stage, large tumor, suboptimal surgery, metastasis and LVSI were associated with unfavourable prognosis in LMS. The grade of tumor and positive margins were associated with an unfavourable prognosis in ESS. This study emphasises the role of multi-modality treatment in the form of Surgery, Radiation and chemotherapy.

PO-1429 Updated results of toxicity and clinical outcome in carcinoma cervix treated with IG-IMRT and IGBT

V.K. Mishra 1 , M. Rastogi 1 , A.K. Gandhi 1 , R. Khurana 1 , R. Hadi 2 , S. Sapru 1 , S.P. Mishra 1 , A.K. Srivastava 1 , A. Bharati 1 , N. Singh 3

1 Dr Ram Manohar Lohia Institute of Medical Sciences , Department of Radiation Oncology , Lucknow , India; 2 Dr Ram Manohar Lohia Institute of Medical Sciences , Department of Radiation Oncology , Lucknow , India; 3 Dr Ram Manohar Lohia Institute of Medical Sciences , Department of Obstetrics and Gynecology , Lucknow , India Purpose or Objective To evaluate the clinical outcome and toxicity profiles in patients with locally advanced carcinoma cervix (LACC) treated with image guided intensity-modulated radiation therapy (IG-IMRT) and image-guided brachytherapy (IGBT). Materials and Methods Between December 2019-November 2021, 25 patients of squamous cell carcinoma cervix with stage IB2-IIIC1 (FIGO 2018) were recruited in to this single arm prospective interventional study (CTRI/2020/08/027434). Whole pelvis IG-IMRT was delivered to a dose of 45Gy in 25 fractions with daily KV-CBCT (IIIC1 patients received 55 Gray in 25 fractions as nodal