ESTRO 2023 - Abstract Book

S394

Sunday 14 May 2023

ESTRO 2023

Conclusion This randomized trial showed significantly reduced patient discomfort, anxiety and pain for the use of open-face masks as compared to traditional closed-face masks. No significant difference in intra-fractional stability was observed. Open-face masks could be considered as the preferred method of immobilization for fractionated cranial radiotherapy. PD-0486 Evaluation of patient reported toxicities and the information we provide to glioblastoma patients. S. Fernandez 1 , F. Boele 2,3 , S. Short 4,5 1 Leeds Cancer Centre, St. James's University Hospital, The Leeds Teaching Hospitals NHS Trust, Research and Innovation, Leeds, United Kingdom; 2 Leeds Institute of Medical Research at St. James's, St. James’s University Hospital, University of Leeds, Leeds, United Kingdom; 3 Faculty of Medicine and Health, Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom; 4 Leeds Cancer Centre, St. James’s University Hospital, The Leeds Teaching Hospitals NHS Trust, Clinical Oncology, Leeds, United Kingdom; 5 Leeds Institute of Medical Research at St. James’s, St James’s University Hospital, University of Leeds, Leeds, United Kingdom Purpose or Objective Radiotherapy is a crucial treatment for patients with glioblastoma, but results in acute toxicities which can hamper their quality of life. Ensuring patients are provided with the most up-to-date evidence related to their individual trajectory is crucial to positive patient engagement and understanding. Patient-reported outcomes and in-depth information about their lived experience of treatment for glioblastoma are critical to inform high quality information materials. The aim of this project was to collect prospective, real-time data to determine if the chemo-radiotherapy pre-treatment information materials we provide to our patients need to be updated. Materials and Methods A prospective, service evaluation of patients with glioblastoma, eligible for the Stupp protocol, was conducted. A repeat cross-sectional, qualitative design was followed whereby individuals were interviewed at specific time points in the treatment pathway. These were defined as prior to radiotherapy (following planning scan and mould room); during radiotherapy (week 2) and post radiotherapy (4-6 weeks post radiotherapy). Patients and their caregivers were invited to participate in face-to-face, semi-structured interviews. Interviews were recorded, transcribed verbatim and thematically analysed. Results In total, nineteen patients with a confirmed diagnosis of glioblastoma and twelve caregivers consented for interview (n=9/n=5 prior to RT, n=5/n=4 during RT, n=5/n=3 post RT). Three main themes emerged. (1) Enhancing public awareness. Responses indicated that headway could be made in educating patients more efficiently in terms of what chemo radiotherapy related toxicities to expect. (2) Individual patient expectation. The majority of patients raised concern regarding insufficient detail of chemo-radiotherapy related toxicities, with some patients expressing fear of the unexpected. (3) Impact of cancer treatment on daily life. Generally, patients and caregivers indicated that information booklets should provide clearer information on the impact of toxicities on patients’ and caregivers’ daily lives, at differing stages of treatment. Conclusion Patients and their caregivers provided constructive responses in relation to wanting more enhanced detail surrounding expected toxicities, toxicity severity and impact on daily life. All participants expressed wanting more detail and information on the probability of likely toxicities to be experienced during and after chemo-radiotherapy, as current pre treatment information given might be too generalised. Utilising patient and caregiver experiences from qualitative interviews to improve the advice we give and to support treatment toxicities, is critical to managing expectations during chemo-radiotherapy. These results will be used to update patient and caregiver information materials, but further detailed investigation is required. PD-0487 On the use of calming video content during MR-linac treatments: gimmick or game-changer? J. Westerhoff 1 , P.T.S. Borman 1 , R.H.A. Rutgers 1 , B.W. Raaymakers 1 , H.M. Verkooijen 1 , M.F. Fast 1 1 University Medical Centre Utrecht, Division of Imaging and Oncology, Utrecht, The Netherlands Purpose or Objective Since the advent of hybrid MRI with a linear accelerator (MR-linac) to deliver MR-guided radiotherapy (MRgRT), concerns were voiced regarding patient experience. A confined bore, increased treatment times and increased noise could negatively impact patients. The aim of this study is to determine patient experience and anxiety during treatment on the MR-linac when offered calming video content.

Materials and Methods