ESTRO 2024 - Abstract Book

S1007

Clinical - Gynaecology

ESTRO 2024

Conclusion:

We have identified five ART approaches for cervical cancer: reactive and scheduled, ITV-based LOP, fixed margin LOP, and real-time adaptation using ETHOS and MR-guidance. The heterogeneity of approaches, even within the same ART category, and varied reporting of dosimetric benefits, adaptation triggering criteria, frequency of adaptation, and required resources, made it challenging to identify the optimal ART strategy for cervical cancer. The LOP-based ITV approach requires intensive resource allocation for imaging, interpolation software, and multiple planning but is the most widely used clinically. However, there remains limited clinical data available to demonstrate its benefits to patients.

Keywords: Cervix cancer, ART, Organ motion

References:

1. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. The BMJ. 2021 Mar 29;372.

2. On target 2: updated guidance for image-guided radiotherapy Radiotherapy Board [Internet]. 2021. Available from: www.rcr.ac.uk

3. Lim K, Stewart J, Kelly V, Xie J, Brock KK, Moseley J, et al. Dosimetrically triggered adaptive intensity modulated radiation therapy for cervical cancer. Int J Radiat Oncol Biol Phys. 2014 Sep 1;90(1):147–54.

Made with FlippingBook - Online Brochure Maker