ESTRO 2024 - Abstract Book

S1021

Clinical - Gynaecology

ESTRO 2024

EM03

57

IIB

SCC, HPV+

81.7

60.6

CR

Table 1. Patient demographics

EM04

52

IIIC1

AC, HPV+

60.5

60.3

PR

Overall, ADC and R2* increased from S1 to S3 (Figures 1 and 2, p<0.05). ADC increased from S1 to S2 to S3 for all patients, however in R2* three patients had reduction from S1 to S2, and 2 patients between S2 and S3. ADC and R2* at S1 are positively skewed, reducing in skewness from S1 to S3 (p<0.05). Kurtosis also

EM05

81

IIB

SCC, HPV+

47.1

68.2

CR

EM07

46

IIA

SCC, HPV+

42.4

79.0

CR

EM08

42

IIIC1

SCC, HPV+

171.2

PR

80.7

EM09

72

IVA

SCC, HPV+

56.9

78.3

CR

EM11

66

IIIC2

SCC, HPV+

67.1

57.5

CR

EM12

60

IIB

AC, HPV+

29.6

82.8

CR

EM13

47

IIIC1

SCC, HPV+

43.2

73.2

CR

reduced for both ADC and R2* from S1 to S3 (p<0.05).

-3 mm 2 /s)

-1 )

Figure 1. ADC med (x 10

Figure 2. R2*

med (s

Higher ADC med at S1 was associated with lower ΔADC S2S3 and ΔADC S1S3 (r=-0.61, -0.55 respectively).

Higher R2* med at S1 was negatively correlated with ΔR2* S1S3 (r=-0.65, p<0.05), and at S3 positively correlated with ΔR2* S1S3 (r=0.76, p<0.02).

TVRR was higher between S2 and S3 compared to S1 and S2 (p<0.05), with volume at S1 correlating with volume at S3 (r=0.72, p<0.02). Only ADC low correlated with TVRR, with increasing ΔADC lowS1S2 associated with increased TVRR S1S2 .