ESTRO 2024 - Abstract Book

S1163

Clinical - Haematology

ESTRO 2024

Conclusion:

Our results indicated that moderate-dose radiotherapy provides excellent disease control and few side effects for patients with newly diagnosed or antibiotics-unresponsive MALT lymphoma. Further investigation of biological factors that are associated with local or distant failure after radiotherapy is warranted.

Keywords: Radiotherapy, MALT lymphoma

References:

Ref. [1]. Kuo SH, Yeh KH, Wu MS, Lin CW, Wei MF, Liou JM, Wang HP, Chen LT, Cheng AL. First-line antibiotic therapy in Helicobacter pylori-negative low-grade gastric mucosa-associated lymphoid tissue lymphoma. Sci Rep. 2017 Oct 30;7(1):14333. Ref. [2]. Yao M, Liao SL, Lin CW, Wang CP, Ma WL, Wei YH, Liou JM, Wang IJ, Cheng AL, Kuo SH. First-line antibiotic treatment in patients with localized extragastric mucosa-associated lymphoid tissue lymphoma. EJHaem. 2022 Nov 6;4(1):55-66.

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Long-term outcomes of total skin electron beam therapy for mycosis fungoides/Sezary syndrome

Raquel Benlloch Rodríguez, Irma Zapata Paz, Jesús Romero Fernández, Marta López Valcárcel, Sofía Córdoba Largo, María Hernández Miguel, Beatriz Gil Haro, Sofía Santana Jiménez, Cristina De la Fuente Alonso, Sara Pérez Mata, Javier Martínez Paredes, María Isabel García Berrocal, Joaquín Velasco Jiménez

Hospital Universitario Puerta de Hierro, Radiation Oncology, Madrid, Spain

Purpose/Objective:

Mycosis fungoides (MF)/Sezary syndrome (SS) are the most common subtype of cutaneous T-cell lymphoma. Total skin electron beam therapy (TSEBT) is an useful skin-directed treatment and can be used either as an exclusive treatment modality or as part of a multimodal strategy for multiple lesions. For a small proportion of patients with SS, intensive haematopoietic stem cell transplantation (HSCT) is a potentially curative treatment option. In some cases, TSEBT can be used as bridge to HSCT. We aimed to evaluate long-term outcomes and side effects in patients with MF/SS treated with total skin electron beam therapy (TSEBT) in a single institution.

Material/Methods: