ESTRO 2024 - Abstract Book

S1212

Clinical - Head & neck

ESTRO 2024

Conclusion:

In our cohort, elevated levels of intratumoral heterogeneity, indicated by the radiomic features GLRLM_GLNU, GLSZM_GLNU, and NGTDM_Busyness, were associated with a higher risk of mortality within two years post-reRT. These radiomic indicators could serve as valuable tools for identifying patients most likely to benefit from reRT in terms of survival, thereby enabling more effective and individualized treatment strategies.

Keywords: Reirradiation, Radiomic, Overall Survival

References:

1. Lee J, Shin I-S, Kim WC, et al. Reirradiation with intensity-modulated radiation therapy for recurrent or secondary head and neck cancer: Meta-analysis and systematic review. Head Neck. 2020;42:2473 – 2485.

2. Ward MC, Riaz N, Caudell JJ, et al. Refining Patient Selection for Reirradiation of Head and Neck Squamous Carcinoma in the IMRT Era: A Multi-institution Cohort Study by the MIRI Collaborative. International Journal of Radiation Oncology*Biology*Physics. 2018;100:586 – 594.

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Classifying patterns of locoregional failure: Cambridge University Hospitals head-and-neck dataset

Ceilidh Welsh 1 , Elinor R. Gatfield 2 , Aviva Grisby 2 , Karl Harrison 3 , Andrew Hoole 4 , Sejal Karmarkar 5 , Annabel Follows 5 , Heather Keenan 6 , Rebecca Sen 2 , Louisa Stockton 2 , Marcos Martinez Del Pero 2 , Daniel Scoffings 7 , Richard Benson 2 , William Ince 2 , Raj Jena 2 , Gillian C. Barnett 2 1 Univeristy of Cambridge, Department of Oncology, Cambridge, United Kingdom. 2 Cambridge University Hospitals NHS Trust, Department of Oncology, Cambridge, United Kingdom. 3 University of Cambridge, Cavendish Laboratory, Cambridge, United Kingdom. 4 Cambridge University Hospitals NHS Trust, Department of Medical Physics,