ESTRO 2024 - Abstract Book

S1230

Clinical - Head & neck

ESTRO 2024

Conclusion:

Regional lymph node metastases are common in patients first diagnosed with hypopharyngeal and laryngeal SCC. The highest rates of positive LNLs are in levels II and III. Detailed reporting of LNL involvement and risk prediction of lymph node metastases in patients diagnosed with hypopharyngeal or laryngeal SCC may contribute to personalization of elective nodal CTV and/or neck dissection, depending on involvement of adjacent LNLs and clinicopathological factors.

Keywords: Lymphatic metastasis, hypopharynx, larynx

References:

1. Biau J, Lapeyre M, Troussier I, Budach W, Giralt J, Grau C, et al. Selection of lymph node target volumes for definitive head and neck radiation therapy: a 2019 Update. Radiother Oncol. 2019;134:1-9.

2. Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, et al. Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines. Radiother Oncol. 2014;110(1):172-81. 3. Machtay M, Moughan J, Trotti A, Garden AS, Weber RS, Cooper JS, et al. Factors associated with severe late toxicity after concurrent chemoradiation for locally advanced head and neck cancer: an RTOG analysis. J Clin Oncol. 2008;26(21):3582-9. 4. Shang J, Gu J, Han Q, Xu Y, Yu X, Wang K. Chemoradiotherapy is superior to radiotherapy alone after surgery in advanced squamous cell carcinoma of the head and neck: a systematic review and meta-analysis. Int J Clin Exp Med. 2014;7(9):2478-87. 5. Ludwig R, Hoffmann JM, Pouymayou B, Däppen MB, Morand G, Guckenberger M, et al. Detailed patient-individual reporting of lymph node involvement in oropharyngeal squamous cell carcinoma with an online interface. Radiother Oncol. 2022;169:1-7.