ESTRO 2024 - Abstract Book

S1347

Clinical - Head & neck

ESTRO 2024

to reduce OAR doses without compromising on PTV coverage and worsening dose to other OARs, leading to improved treatment plan quality and the delivery of optimal OAR doses to patients.

Keywords: Support Vector Data Description, Control Chart

References:

1. Tax D.M., Duin R.P. Support Vector Data Description. Machine Learning . 2004; 54: 45 – 66.

2. Roy A, Cutright D, Gopalakrishnan M, Yeh AB, Mittal BB. A Risk-Adjusted Control Chart to Evaluate Intensity Modulated Radiation Therapy Plan Quality. Adv Radiat Oncol . 2019; 5(5): 1032-1041.

3. Gani W, Taleb H, Limam M. An assessment of the kernel-distance-based multivariate control chart through an industrial application. Qual Reliab Eng Int . 2011; 27: 391-401.

1847

Digital Poster

Stereotactic Radiotherapy and Radiosurgery vs Fractionated Radiotherapy for HN Paragangliomas

Laura Giannini 1 , Alfio Spina 2 , Miriam Torrisi 1 , Denatoni Chiara Lucrezia 1 , Fodor Andrei 1 , Nicola Boari 2 , Lucia Perna 3 , Carmen Gigliotti 3 , Michele Bailo 2 , Martina Midulla 1 , Roberta Tummineri 1 , Filippo Gagliardi 2 , Italo Dell'Oca 1 , Antonella Del vecchio 3 , Stefano Arcangeli 4 , Pietro Mortini 2 , Nadia Di Muzio 1 1 IRCCS San Raffale, Radiation Oncology, Milano, Italy. 2 IRCCS San Raffale, Neurosurgery, Milano, Italy. 3 IRCCS San Raffale, Physics, Milano, Italy. 4 IRCCS San Gerardo dei Tintori, Radiation Oncology, Monza, Italy

Purpose/Objective:

Head and Neck paragangliomas (HNPGL) are rare, mostly benign, slow growing neoplasms. The aim of this study is to evaluate local tumor control and toxicity of radiotherapy treatments delivered in our Center.

Material/Methods:

From 07/2002-01/2023 50 patients (pts) with 58 HNPGL were treated with radiotherapy (RT). Eleven treatments were delivered by TomoTherapy® (Accuray, Maddison, WI) (TT), with a median dose of 50 Gy (45-60). Fractionated external beam irradiation was used to treat larger tumor volumes. Eleven treatments were delivered by Cyber Knife ™ (Accuray, Sunnyvale, CA) (CK), with a median dose of 26 Gy (25-30), in a median of 5 (1-5) fractions, at a median prescription isodose of 78 % (69-85). Thirty treatments were delivered by Gamma Knife Perfexion ™ (Elekta, Stockholm, Sweden) (GK), with a median dose of 16 Gy (13-18); the median isodose line was 50%. Five of the 50 pts