ESTRO 2024 - Abstract Book

S135

Invited Speaker

ESTRO 2024

Refresher and Innovations in Gynaecological Brachytherapy: A RTT's Perspective

Bernd Wisgrill

University Clinic for Radiooncology, General Hospital Vienna, Brachytherapy, Vienna, Austria

Abstract:

Brachytherapy is an effective and indispensable method for the treatment of gynaecological and cervical cancer. This refresher and update session focuses on RTTs and provides a comprehensive overview of developments in gynaecological brachytherapy. The presentation highlights the specific challenges faced by RTTs in brachytherapy, including the use of imaging techniques, applicators, treatment planning and workflow. Current methods in the workflow of RTTs and their adaptation to new technologies will be discussed. Special attention is given to innovative applicators that could open new possibilities in brachytherapy, such as the Venezia-Applicator and other novel designs. These applicators could enhance the treatment of tumours by enabling a precise placement of the radiation source and enhanced dose distributions. The presentation provides an overview of these advanced applicators, shows their useage in the clinical setting and discusses their impact on patientcare within the realm of RTT activities. This session will discuss methods for optimising workflows to ensure precise and safe brachytherapy treatment and the integration of innovative applicators into clinical practice. Relevant adjustments to imaging, planning, and reconstruction within RTT activities are also discussed. Examples will be used to present the impact of these new technologies and provide insights into their practical application.

3579

Digital twins for personalised radiation oncology

Heiko Enderling

The University of Texas MD Anderson Cancer Center, Radiation Oncology, Houston, USA

Abstract:

To personalize radiation therapy, we must give the right dose and dose fractionation, at the right time, dynamically adapted, to best harness the radiobiological effects of radiation as well as synergy with the patient immune system. I present latest developments in the mathematical and computational modelling in radiation oncology to develop digital twins – constructs that mimic the structure and behavior of the patient and the tumor to make predictions and inform decisions that realize value. I present different simple approaches to build predictive pipelines and how to integrate those into clinical decision making towards the concept of real-time adaptive personalized radiation treatments.

3580

MRI-guided radiotherapy for prostate cancer and other pelvic tumours