ESTRO 2024 - Abstract Book

S143 ESTRO 2024 1 Applied Radiation Therapy Trinity (ARTT), Discipline of Radiation Therapy, School of Medicine, Trinity St. James's Cancer Institute, Trinity College Dublin, University of Dublin, Dublin, Ireland. 2 UZ, -, Gent, Belgium. 3 University of Applied Sciences InHolland, -, Haarlem, Netherlands. 4 Cancer Patients Europe, -, Brussels, Italy. 5 East Galway & Midlands Cancer Support, -, Ballinasloe, Co Galway, Ireland. 6 Department of Translational Medicine (DIMET), University of Eastern Piedmont and Department of Radiation Oncology, 'Maggiore della Carità' University Hospital, Novara, Italy. 7 The Royal Marsden, NHS Foundation Trust, London, United Kingdom. 8 Department of Radiation Oncology, Medical University of Vienna, Vienna, Austria. 9 NHS England, -, Leeds, United Kingdom. 10 Division of Radiation Oncology, IEO, European Institute of Oncology, IRCCS,, Milan, Italy. 11 Department of Oncology and Hemato Oncology, University of Milan, Milan, Italy. 12 Department of Radiotherapy, The Netherlands Cancer Institute- Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands. 13 University Clinic for Radiotherapy and RadioOncology of the PMU, County Hospital Salzburg, Salzburg, Austria Invited Speaker Despite huge technological advances in external beam radiation therapy, there is still a significant proportion of patients experiencing radiation-induced skin reactions. An international writing group consisting of 12 experts from radiotherapy and two patient representatives composed a recommendation document for the management of radiodermatitis (RID). The consensus for these recommendations was generated based on a number of international guidelines and supplemented with evidence based on review articles on the topic. These recommendations focus on the prevention and management of early stages of RID by avoiding skin trauma as well as maintaining hygiene and moving more towards addressing pain and inflammation in higher grades. The current literature refutes some of the traditional recommendations especially restricting washing as well as the use of deodorant or the potential dose build-up of lotions which has been included and rectified in recent guidelines. However, anecdotally some of these are still used, underpinning the need for published evidence-based recommendations. In addition to providing recommendations on the prevention and management of RID, the importance of grading the severity, including a baseline assessment is presented. Consideration of possible risk factors and communication within the multidisciplinary team is described. The benefit of clear, non-contradictory communication with the patients, as well as patient involvement (e.g. PROMs or similar), is highlighted. Furthermore, the importance of recognising different skin types and skin tones, and the impact on how RID changes these in their appearance is stressed. The writing group provides recommendations, referencing the supporting literature and its hierarchy of evidence. However, the writing group acknowledge that there is still a lack of high-level evidence, especially for agent-specific recommendations. Abstract:

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ESTRO-EANO guideline on target delineation and radiotherapy details for glioblastoma

Maximilian Niyazi

University Hospital Tübingen, Department of Radiation Oncology, Tübingen, Germany

Abstract: