ESTRO 2024 - Abstract Book

S1661

Clinical - Lung

ESTRO 2024

Maximum relative dose difference with wCT (%)

Median relative dose difference with wCT (%)

Mean relative dose difference with wCT (%)

Minimum relative dose difference with wCT (%)

DVH Parameter

Structure

Dmean% [Gy]

0.29

0.40

0.04

1.19

Dmax% [Gy]

0.56

0.85

0.16

3.03

D98 [Gy]

0.35

0.44

0.06

1.38

D95 [Gy]

0.45

0.52

0.10

1.57

PTV

D50 [Gy]

0.28

0.44

0.03

1.39

D5 [Gy]

0.25

0.52

0.01

2.01

D2 [Gy]

0.26

0.57

0.00

2.14

Table 1: Overall dosimetric results comparing synthetic CTs and warped CTs

Conclusion:

In this work, we have demonstrated the feasibility of using artificial intelligence to transform CBCT images to high resolution CT. The present evaluation demonstrated the non-inferiority of using CBCT-based synthetic CT for thoracic cancer treatment planning in terms of dosimetric measures. Next steps will include the integration of this work in the context of an effective implementation of an adaptive workflow from OARs annotation to full scale dose simulation and replanning.

Keywords: Adaptive RT, Synthetic-CT, Dose calculation

1398

Digital Poster

Baseline radiomic features for outcome modeling in early-stage NSCLC candidates to SBRT

Stefania Volpe 1,2 , Aurora Gaeta 3 , Alessia Casbarra 1 , Jessica Franzetti 1 , Anna M Camarda 1 , Federico Mastroleo 1,4 , Gaia Piperno 1 , Mattia Zaffaroni 1 , Maria G Vincini 1 , Sara Raimondi 3 , Francesca Botta 3 , Lars J Isaksson 1 , Sara Gandini 3 , Marta Cremonesi 5 , Roberto Orecchia 6 , Barbara A Jereczek-Fossa 1,2 1 European Institute of Oncology IRCCS, Radiation Oncology, Milan, Italy. 2 University of Milan, Department of Oncology and Experimental Oncology, Milan, Italy. 3 European Institute of Oncology IRCCS, Experimental Oncology,