ESTRO 2024 - Abstract Book

S161

Brachytherapy - Breast

ESTRO 2024

principle, it can be readily adopted in clinical practice and thus holds great potential for significant time savings while increasing reconstruction accuracy in treatment planning of interstitial breast brachytherapy.

Keywords: implant reconstruction, EM tracking, automation

References:

[1] Guinot JL, Gonzalez-Perez V, Meszaros N, Major T, Najjari-Jamal D, Gutierrez-Miguelez C, et al. Very accelerated partial breast irradiation Phase I&II multicenter trial (VAPBI): Feasibility and early results. Brachytherapy. 2021;20:332-8. [2] Yashar CM, Khan AJ, Haffty BG, Chen PY, Yehia ZA, Vicini FA, et al. Three-Fraction TRIUMPH-T Brachytherapy for Delivery of APBI Offers Effective Disease Control With Minimal Late Toxicity. International Journal of Radiation Oncology*Biology*Physics. 2021;111:S7. [3] Khan AJ, Chen PY, Yashar C, Poppe MM, Li L, Abou Yehia Z, et al. Three-Fraction Accelerated Partial Breast Irradiation (APBI) Delivered With Brachytherapy Applicators Is Feasible and Safe: First Results From the TRIUMPH T Trial. International Journal of Radiation Oncology*Biology*Physics. 2019;104:67-74. [4] Strnad V, Major T, Polgar C, Lotter M, Guinot J-L, Gutierrez-Miguelez C, et al. ESTRO-ACROP guideline: Interstitial multi-catheter breast brachytherapy as Accelerated Partial Breast Irradiation alone or as boost – GEC-ESTRO Breast Cancer Working Group practical recommendations. Radiotherapy and Oncology. 2018;128:411-20. [5] Kallis K, Kaltsas T, Kreppner S, Lotter M, Strnad V, Fietkau R, et al. Impact of inter- and intra-observer variabilities of catheter reconstruction on multi-catheter interstitial brachytherapy of breast cancer patients. Radiotherapy and Oncology. 2019;135:25-32.

2853

Proffered Paper

Excellent local control after intensification with HDR-BT boost in locally advanced breast cancer.

Irene Martínez 1 , Ignacio Visus 1 , Naiara Fuentemilla 2 , Pellejero Santiago 2 , Paola Jablonska 1 , Sonia Flamarique 1 , Raquel Villanueva 1 , Erkuden Burillo 1 , Amaya Sola 1 , Ana Manterola 1 , Ujué Ruiz 1 , Maria Isabel Martínez 1 , Patricia Lorenzana 1 , Víctor De La Llana 2 , Libe Amondarain 1 , Darwin Pozo 1 , Marta Barrado 1 , Paola Navarrete 1 , Pilar Almeida 1 , Inés Villafranca 1 , Elena Villafranca 1 1 Hospital Universitario de Navarra, Radiation Oncology, Pamplona, Spain. 2 Hospital Universitario de Navarra, Medical Phycisist, Pamplona, Spain

Purpose/Objective:

Locally advanced breast cancer patients are at high risk of local and systemic relapse.

The aim of our study was to analyze the impact of intensification using high-dose brachytherapy (HD-BT) boost delivered to the tumor bed in patients with locally advanced breast cancer, who underwent neoadjuvant