ESTRO 2024 - Abstract Book

S1689

Clinical - Lung

ESTRO 2024

Conclusion:

This prospective trial demonstrated the benefit of CPAP in distinguishing the boundaries between the adjacent structures and the tumors in the lower lung and reducing respiration-induced tumor motion, which is expected to increase certainty in target volume delineation in patients who undergo lung SABR. CPAP-induced lung expansion leads to a decrease in overall lung parenchymal density, resulting in clearer tumor delineation and a reduction in radiation exposure to the normal lung parenchyma. The dosimetric analysis revealed significant benefits in radiation exposure of organs at risk with the use of CPAP. CPAP was found to be a safe, reasonable, and well tolerated approach for patients with no severe toxicity. Further investigation is warranted to explore the role of CPAP as a strategy for respiratory motion management.

Keywords: lung cancer, SBRT, motion management

1725

Digital Poster

Toxicity and efficacy of SABR for central lung tumours: a single institution experience

Bailey Smith 1 , Rachael Wooder 2 , Kathryn Banfill 3 , Claire Barker 3 , Neil Bayman 3 , Clara Chan 3 , Joanna Coote 3 , Corinne Faivre-Finn 4,3 , Margaret Harris 3 , Paul Hoey 5 , Jennifer King 3 , Laura Pemberton 3 , Hamid Sheikh 3 , Okezie Ucheikonne 5 , Philip Whitehurst 6 , David Woolf 3 1 The University of Manchester, School of Medical Sciences, Manchester, United Kingdom. 2 The Christie NHS Foundation Trust, Radiotherapy Services, Manchester, United Kingdom. 3 The Christie NHS Foundation Trust, Clinical Oncology, Manchester, United Kingdom. 4 The University of Manchester, Division of Cancer Sciences, Manchester, United Kingdom. 5 The Christie NHS Foundation Trust, Digital Services, Manchester, United Kingdom. 6 The Christie NHS Foundation Trust, CMPE Radiotherapy Physics, Manchester, United Kingdom

Purpose/Objective: