ESTRO 2024 - Abstract Book

S1810

Clinical - Lung

ESTRO 2024

Conclusion:

This case study reports the first in human BgRT delivery using the RefleXion X1 system in a clinical setting. The system's ability to deliver radiotherapy autonomously using real-time PET imaging with radiation delivery opens new possibilities for optimizing treatment accuracy and safety. Further investigations are warranted to assess the broader applicability of BgRT and its impact on patient outcomes.

Keywords: Biology-guided Radiotherapy, BgRT, SABR

References:

1- Oderinde OM, Shirvani SM, Olcott PD, Kuduvalli G, Mazin S, Larkin D. The technical design and concept of a PET/CT linac for biology-guided radiotherapy. Clin Transl Radiat Oncol. 2021;29:106-112. doi:10.1016/j.ctro.2021.04.003

2- Han B, Capaldi D, Kovalchuk N, et al. Beam commissioning of the first clinical biology-guided radiotherapy system. J Appl Clin Med Phys. 2022;23(6). doi:10.1002/acm2.13607

3- Simiele E, Capaldi D, Breitkreutz D, et al. Treatment planning system commissioning of the first clinical biology guided radiotherapy machine. J Appl Clin Med Phys. 2022;23(8). doi:10.1002/acm2.13638

4- Hu Z, Bieniosek M, Ferri V, et al. Image-mode performance characterisation of a positron emission tomography subsystem designed for Biology-guided radiotherapy (BgRT). British Journal of Radiology. 2023;96(1141). doi:10.1259/bjr.20220387

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Digital Poster

NSCLC Electronic Health Records Analysis by Named Entity Recognition in Italian Clinical Reports

Aurelia Iurato 1 , Edy Ippolito 2,1 , Carlo Greco 2,1 , Claudia Tacconi 2 , Michele Fiore 3,4 , Marianna Miele 1 , Luca E Trodella 1 , Vincenzo Palumbo 2 , Rosa Sicilia 5 , Domenico Paolo 5 , Paolo Soda 6 , Sara Ramella 2,1