ESTRO 2024 - Abstract Book

S1821

Clinical - Lung

ESTRO 2024

Our open-source algorithms could be a useful tool to support the implementation of PET imaging and to facilitate the evaluation of its impact on lung cancer clinical practice, from tumor detection to treatment planning and response evaluation.

Keywords: AI, Autocontouring, PET

3210

Digital Poster

When to assess SBRT outcomes for lung nodules? Findings from a single-center study

Elena Galofaro 1 , Lorenzo Vagnoni 1 , Silvia Bisello 1 , Mohamed Vincenzo Agbaje Olufemi 1 , Francesca Cucciarelli 1 , Francesco Fenu 1 , Eleonora Arena 1 , Cristina Mariucci 1 , Valeria Panni 1 , Marco Parisotto 2 , Marco Valenti 2 , Giovanna Mantello 1 1 Azienda Ospedaliero Universitaria delle Marche, Radiotherapy Department, Ancona, Italy. 2 Azienda Ospedaliero Universitaria delle Marche, Physics Department, Ancona, Italy

Purpose/Objective:

Although stereotactic radiotherapy (SBRT) has been shown in numerous studies to be a very valuable modern technique to achieve good local control and improve survival in pulmonary metastases or primary pulmonary nodules, the timing and modalities for assessing response to radiotherapy are not well defined. The aim of our study is to present the results of a group of patients treated at our center.

Material/Methods:

Patients treated for pulmonary metastases or primary lesions between 2019 and 2022 were included in the analysis. Data related to patients' characteristics and radiotherapy (RT) dose fractionations were collected.

Response to treatment was assessed at 3-month intervals after the end of treatment (0-3 months, 4-6 months, 7-9 months, 10-12 months, > 12 months) and evaluated by size according to RECIST criteria and metabolic response considering SUV reduction (PERCIST criteria).

The complete response (CR), partial response (PR), and disease stability (SD) of these lesions were assessed.

Results:

Fifty-seven lesions were evaluated. Thirty-seven of these lesions had at least 2 radiological examinations (CT and/or PET-CT) within 1 year (with the first radiological examination occurring at least 3 months after SBRT), so they were included in the response rate analysis.