ESTRO 2024 - Abstract Book

S1850

Clinical - Mixed sites, palliation

ESTRO 2024

and F (56%). The percentages of patients experiencing no pain after three months were: A (13%), B (15%), C (20%), D (9%), E (7%), and F (10%). The overall improvement in the CS score (primary outcome), expressed in percentage, over three and six months, respectively, for each arm was as follows: A (29.9% and 32%), B (23.9% and 32%), C (26.4% and 34%), D (21.6% and 30%), E (23.3% and 36%), and F (18.9% and 27%).

Conclusion:

Despite a slightly higher number of reirradiations in the experimental arms compared to the standard arm, a single fraction irradiation seems to be a viable option, providing comparable and sufficient pain relief after 3 months. There was no clear advantage noted for either the single-fraction arms, longer follow-up is required to conclusively address this question. Based on this preliminary results, it appears that single-fraction HSS radiotherapy could be a favorable choice for a significant number of patients, reducing the workload on healthcare personnel and offering an attractive cost-benefit ratio.

Keywords: heel spur,antiinflamatory radiation,clinical trial

References:

Buchbinder R. Clinical practice. Plantar fasciitis. N Engl J Med 2004;350:2159-2166

Heyd R, et al. Radiation therapy for painful heel spurs: results of a prospective randomized study. Strahlenther Onkol. 2007;183:3 – 9.

Niewald M, et al. Randomized,multicenter trial on the effect of radiation therapy on plantar fasciitis (painful heel spur) comparing a standard dose with a very low dose: mature results after 12 months’ follow ‐ up. Int J Radiat Oncol Biol Phys. 2012;84:e455 – e462.

Ott OJ, et al. Radiotherapy for benign calcaneodynia: long ‐ term results of the Erlangen Dose Optimization (EDO) trial. Strahlenther Onkol. 2014;190:671 – 675

Kriz J, et al. Updated strategies in the treatment of benign diseases-a patterns of care study of the german cooperative group on benign diseases. Adv Radiat Oncol 2018;3(3):240-244.

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Poster Discussion

Irradiating patients with progression during ICI triggers abscopal responses and enhances survival

Maike Trommer 1,2,3 , Alexander Rühle 4,5 , Allison Lamrani 6 , Charlotte Schmitter 6 , Justus Kaufmann 7 , Matthias Mäurer 8,9 , Georg Wurschi 8,10 , Ping Jiang 11 , Felix Ehret 12 , Andrea Baehr 13 , Annika Hardt 14 , Raphael Bodensohn 15,16 , Lukas Käsmann 15 , Danny Jazmati 17 , Maria Waltenberger 18,19,20 , Sebastian Neppl 1 , Anna Hagemeier 21 , Julian P. Layer 22,23,24 , Davide Scafa 22,24 , Simone Wegen 1,3