ESTRO 2024 - Abstract Book

S1891

Clinical - Mixed sites, palliation

ESTRO 2024

Conclusion:

In this first-in-human trial of 2D antiscatter grid-based CBCT, an improvement in image quality was observed in vast majority of CBCT scans in the pelvis-lower-abdomen region, when compared to clinical CBCT scans (Fig. 3). This observer study supports the significance of robust scatter mitigation in further improving CBCT image quality. However, when severe motion artifacts are present, the degradation of image quality was driven by motion artifacts rather than scattered radiation. Future work will include quantitative analysis of image quality and expansion of the qCBCT trial to other anatomical regions such as the H&N region.

Keywords: CBCT, quantitative imaging, adaptive RT

1082

Digital Poster

Fractionation in palliative radiotherapy for bone metastases – 5 years of experience in one hospital

Christine Vestergaard Madsen 1 , Rune Slot Thing 2 , Charlotte Kristiansen 1 , Henrik D. Nissen 2 , Martin Berg 2 , Lars Ulrik Fokdal 2 1 Vejle Hospital, University Hospital of Southern Denmark, Department of Oncology, Vejle, Denmark. 2 Vejle Hospital, University Hospital of Southern Denmark, Radiotherapy Research Team, Department of Oncology, Vejle, Denmark

Purpose/Objective:

Radiotherapy (RT) plays an important role in palliative treatment of bone metastases. Although single fraction schedules may be associated with a higher risk for subsequent retreatment to the same site, there is evidence to support that single fraction and fractionated RT schedules deliver equal pain relief in uncomplicated bone metastases. However, the optimal dose and number of fractions in relation to different cancer diagnoses and age are not well defined. This study aims to evaluate the pattern of dose prescription of palliative RT for bone