ESTRO 2024 - Abstract Book

S187

Brachytherapy - GI, paediatric, miscellaneous

ESTRO 2024

1. Walter F, Rottler M, Nierer L, Landry G, Well J, Rogowski P, Mohnike K, Seidensticker M, Ricke J, Belka C, Corradini S. Interstitial High-Dose-Rate Brachytherapy of Liver Metastases in Oligometastatic Patients. Cancers (Basel). 2021 Dec 13;13(24):6250.

2. Kieszko D, Cisek P, Kordzińska-Cisek I, Grzybowska-Szatkowska L. Treatment of hepatic metastases with computed tomography-guided interstitial brachytherapy. Oncol Lett. 2018 Jun;15(6):8717-8722

2445

Digital Poster

Novel Post-operative intraluminal brachytherapy for margin positive hilar cholangiocarcinoma

Prahlad Yathiraj 1 , Monali Puri 1 , Sathish Arjunan 1 , Azmi Kumaravelu 1 , Deepashree Thiruchunapalli 2 , Rajesh Rajalingam 3 , Mohamed Rela 3 1 Dr Rela Institute & Medical Centre, Department of Radiation Oncology, Chennai, India. 2 Dr Rela Institute & Medical Centre, Department of Interventional Radiology, Chennai, India. 3 Dr Rela Institute & Medical Centre, Department of HPB Surgery and Liver Transplantation, Chennai, India

Purpose/Objective:

Achieving an R0 resection in hilar cholangiocarcinomas (HCCA) is a challenge and has proven prognostic for disease-free survival and overall survival.1,2,3 Local progression occurs in more than 33% among patients with R1 resection. 3 Radiotherapy is one among the adjuvant treatment options in the margin positive setting.4 In this novel approach, we aim to analyse if post-operative brachytherapy is safely tolerated, can be followed by full dose chemotherapy (and external radiotherapy when indicated), and if it helps prevent progression at the anastomotic site in locally advanced margin positive HCCAs.

Material/Methods:

Fig.1 - dose distribution seen in saggital section