ESTRO 2024 - Abstract Book

S2304

Clinical - Urology

ESTRO 2024

Considering the interaction between these four important variables, we selected the model stepwisely by AIC (Akaike Information Criterion) and used pn + Sv + Boost + pn:Sv for multiple regression. The estimated hazards were pn: 2.55 (1.01 - 6.41)(p < 0.05, proportionality test 0.46), Sv: 13.25 (1.50 - 116.61)(p < 0.05, test 0.99), boost: 0.39 (0.18 - 0.86)(p < 0.05). , test 0.28) and pn:Sv: 0.13 (0.01 - 1.26)(p < 0.1, test 0.82). The concordance index was 0.67. See Figure.

Conclusion:

Although one institutional and a very small number of patients involved, the intensification of adjuvant radiotherapy added to postoperative radiotherapy for prostate cancer had a good effect. Biological recurrences were expected to be reduced by approximately one-third. In particular, additional radiation should be considered for patients with seminal vesicle invasion (Sv+) or perineural invasion (pn+).

Keywords: postprostatectomy-radiotherapy, boost, Cox-models

243

Poster Discussion

Evaluation of EMBARK criteria patients. Real-world data on prostate cancer biochemical recurrence.

Elena Centelles Hidalgo 1 , Antonio Gomez-Caamano 2 , Sonia Garcia Cabezas 3 , Bernando Herrera 4,5 , Arantxa Tubio Abuin 2 , Juan Adrián Camús Martínez 3 , Fernando Alberca 4,5 , Rafael Ordoñez Marmolejo 6 , Antonio Lazo Prados 6 , Carmen Ibañez Villoslada 7 , María Gómez Aparicio 8 , Victor Duque-Santana 9,10 , Jose María Nieto 11 , Mikel Eguiguren Bastida 12 , Miguel Ángel Berenguer 13 , Antonio Conde Moreno 13 , Raquel García-Gómez 14 , Alai Goñi Ramirez 15 , Leonardo Guerrero 9 , Ángeles Sánchez Galvez 16 , Carmen Vallejo 1 , Asunción Hervás Morón 1 , Sonsoles Sancho García 1 , Fernando López-Campos 1