ESTRO 2024 - Abstract Book

S2406

Clinical - Urology

ESTRO 2024

Results:

We analyzed 381 patients, with pT stage distribution of 18.9% for stage 2, 79.5% for stage 3, and 1.6% for stage 4. The pN stage was 0 in 85.3% and 1 in 14.7% of cases. Younger patient age (1 st quartile: < 62 years) and pN1 stage were independently correlated with worse bRFS and DFS. Additionally, pN1 stage, higher postoperative PSA levels, and higher ISUP grade were linked to worse bRFS. LC was poorer in pN1 patients, but RC was improved in patients who underwent PNI or had preoperative PSA <10 ng/dL. OS was better in patients with pN0 status (compared to pN1) and no prior history of cancer ( Table 1 ).

Conclusion:

Younger patient age is an adverse predictor for both biochemical and clinical recurrences in PCa patients undergoing PORT. These findings underscore the importance of considering age in developing predictive models for this patient population.

Keywords: age, prognostic factor, prostate cancer

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Analysis of Dose-Escalated Stereotactic Body Radiation Therapy in Localized Prostate Cancer

Bichun Xu 1 , Xianzhi Zhao 1,2 , Huojun Zhang 1

1 The First Affiliated Hospital of Naval Medical University, Department of Radiation Oncology, Shanghai, China. 2 the Second Affiliated Hospital of Soochow University, Department of Radiation Oncology, Suzhou, China