ESTRO 2024 - Abstract Book

S2596

Clinical - Urology

ESTRO 2024

The participants were invited to anonymously answer questions regarding the local treatment: 1) the timing of radiotherapy 2) the target volume 3) the optimal dose and the metastasis-directed treatment: 4) the indication of radiotherapy 5) the timing 6) the target volume 7) the treatment technique.

Results:

A total of 32 radiation oncologists completed the survey (Table).

For local treatment, 17 participants (53.1%) proposed to start radiotherapy only in case of response to systemic treatment. For 20 participants (62.5%)) the target volume should include the prostate, the seminal vesicles, all involved lymph nodes, and pelvic prophylactic irradiation. The irradiation should be indicated with conventional fractionation for 22 participants (68.8%) with dose escalation for 15 participants (56,9%). For metastasis-directed treatment, 30 RO (93.8%) proposed to deliver radiotherapy after the local radiotherapy for 18 participants (56.3%). The target volume should encompass all involved sites in metabolic imagery (28 participants; 87.5%) with stereotactic technique (27 participants; 84.4%).

Table: Radiation oncologist answers for different question

Conclusion:

The results of our study show that practices of RO are not always harmonious regarding the radiotherapy of oligometastatic prostate cancer especially for the modalities of local treatment. In addition, and despite the lack of studies supporting the benefit of metastasis-directed radiotherapy for synchronous metastasis in prostate cancer, radiotherapy of metastases was indicated by most participants. These results underline the importance of drafting national recommendations which could help harmonize practices.

Keywords: oligometastatic, local treatment, radiotherapy