ESTRO 2024 - Abstract Book

S2625

Clinical - Urology

ESTRO 2024

Conclusion:

Dose escalated ultra-hypo-fractionated RT using an endo-rectal spacer and urethral sparing technique is associated with favorable long term health related quality of life outcomes and compares favorably with historical data of moderate hypofractionation or standard dose ultra-hypo-fractionated RT.

Keywords: SBRT prostate

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Digital Poster

Profiling PCa pts with BCR in the era of early imaging detection: a ML nomogram

Giulia Marvaso 1,2 , Federico Mastroleo 1,3 , Riccardo Villa 1,2 , Mattia Zaffaroni 1 , Giulia Corrao 1 , Maria Giulia Vincini 1 , Fabio Montrone 4 , Alessandro Magli 5 , Giulio Francolini 6 , Ciro Franzese 7,8 , Luca Nicosia 9 , Francesco Pasqualetti 10 , Luca Trodella 11 , Annamaria Vinciguerra 12 , Salvina Barra 13 , Giorgia Timon 13 , Matteo Augugliaro 14 , Corrado Spatola 15 , Vincenzo Burgio 16 , Marta Scorsetti 7,8 , Stefano Arcangeli 17 , Luca Triggiani 18 , Barbara Alicja Jereczek-Fossa 1,2 1 IEO European Institute of Oncology IRCCS, Division of Radiation Oncology, Milan, Italy. 2 University of Milan, Department of Oncology and Hemato-Oncology, Milan, Italy. 3 University of Piemonte Orientale, Department of Translational Medicine, Novara, Italy. 4 Radiation Oncology Department, Centro di Riferimento Oncologico (CRO), Aviano, Italy. 5 Udine University Hospital, Department of Radiation Oncology,, Udine, Italy. 6 Azienda Ospedaliero Universitaria Careggi, Radiation Oncology Unit, Milan, Italy. 7 IRCCS Humanitas Research Hospital, Department of Radiotherapy and Radiosurgery, Rozzano, Italy. 8 Humanitas University, Department of Biomedical Sciences, Pieve Emanuele, Italy. 9 IRCCS Sacro Cuore Don Calabria Hospital, Radiation Oncology Department, Negrar di Valpolicella, Italy. 10 Azienda Ospedaliero Universitaria Pisana, Radiation Oncology Unit, Pisa, Italy. 11 Campus Bio-Medico University, Department of Radiation Oncology, Rome, Italy. 12 SS. Annunziata Hospital, “G. D’Annunzio” University of Chieti, Radiation Oncology Unit, Chieti, Italy. 13 IRCCS Ospedale Policlinico San Martino, Department of Radiation Oncology, Genova, Italy. 14 Azienda USL-IRCCS, Radiation Oncology Unit, Reggio Emilia, Italy. 15 Policlinico di Catania, Division of Radiation Oncology, Catania, Italy. 16 Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo, Division of Radiation Oncology, Alessandria, Italy. 17 San Gerardo Hospital, Department of Radiation Oncology, Monza, Italy. 18 University and Spedali Civili Hospital, Radiation Oncology Department, Brescia, Italy

Purpose/Objective:

Although radical prostatectomy (RP) represents a curative treatment, 44% of pts experience BCR at least 6 months after surgery. While in low-risk pts the interval between surgery and BCR does not influence mortality, in pts with unfavorable disease characteristics early disease recurrence increases mortality risk. Aim of this study is to create a predictive model to identify the category of pts most at risk of distant metastasis to undergo early imaging investigations.